Grand Theft Auto Online’sLos Santos Drug Wars update includes six missions labeled First Dose. The last of these is First Dose 6 - Off The Rails. If you have made it this far, you are likely adept at combat and can handle a big gunfight by yourself. However, this last mission is divided into several distinct parts with challenges the prior five missions do not have.

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Most notably, it starts with a big stealth segment, followed by a race against the clock. It then ends with a big firefight by a crashed train. To go through this mission smoothly, simply follow the walkthrough below.

Preparing For The Mission

Here is what you shouldhave equipped and preparedbefore embarking on the mission:

Once you have all of these, you are all set to actually start the mission.

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First Dose 6 - Off The Rails Walkthrough

The mission starts with youat the Freakshopin an orange jumpsuit and mask. Dax calls, and you aredirected to theHumane Labs and Research facility. Your mission is thesneak through the facility and steal precursor chemicalsfor a new batch of special acid.

The objective is marked on the map in green. You can assault the compound and shoot everything in sight, but astealthy approach is safer and leaves less of a body count.

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Sneaking Through The Compound

Park the caron the road away from the entry gateand walk toward the entrance. When close,go to the left of the booth.This should beoutside the enemy’s cone of vision.You will have no problemapproaching this guard and getting a clean headshotwith the silenced pistol.

Make a right once you pass the gate and hug the wall as you sneak forward. Take a left andshoot the security camerabefore walking past it. Keep walking forward until you reacha point with three guards.

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One guard isabove you on the left,another isloading a truck, and the third isdirectly in front of you. Take outthe one above youfirst, and then theone right in front of you. The one loading the truck will not notice.Sneak forward and thengo up the stairs behind the second guardyou killed.

Withaim assist,getting headshots is simple, even from far away and in the dark. Theauto lock targets the body, so aim up slightly.Go up until the reticle turns white again and then aim down,which should set the reticle right on their head for a one-shot kill.

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At thetop of the stairs turn aroundand head in the direction of the objective via the rooftops.From the roof, you can get a headshot on the guard right in front of the door.If you are quick enough, you canhack the door quickly after killing him. Otherwise, shoot down a few of the other guards in the area toprevent setting off an alarm.

Once inside the compound,the objective is directly in front of you. There are several pairs of guards here who are looking at each other.Killing them while remaining in stealth is tricky, but you can do it while playing solo if youshoot both of them fast enough. As long as they don’t shoot, you will not sound an alarm.

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After clearing this room, you canfind the plans by the entryway where the cargo is held.Photograph them and send them to Dax. Then, you have all the time you need toopen all the boxes and collect the objectives.

Stopping The Train

Here, you have toreach a rail switch and flick the switch before the train passes.Time is actually quite short, so don’t dilly-dally. After youopen the gate to leave the building, a car with enemies approaches.Blow the car up with explosives.

Steal a parked car and drive out of the compound. The easiest way to reach the switching station is todrive on the tracks in front of the train.It leads you directly to the objective.Go inside the booth and activate the switch.

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Once the train crashes you have toget tools from a point marked on the map.Drive to these, pick them up, and thenmake your way to the crash site.

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Extracting The Chemicals

Using the recently acquired tools, you have toopen containers on train cars until you have found all the chemicals.As you make your way from container to container, more enemies come.A helicopterwill occasionally come, which is where yourHoming Launchercomes in handy.

Guards kill you fast, but theydon’t seem to hit you quite as much during the animationof opening the container. Use this to your advantage. Once thecontainer is open, you can use it as cover.Theglowing green areas progressively damageyou too, so don’t linger in them too long.

grand theft auto online outside humane labs building chasing the train

Once you collect all the chemicals, your last objective is tocollect the Brickade 6X6 on the last wagonand drive it back to the Freakshop.It is a slow, cumbersome vehicle, so driving it off the train car is irritating. Youwill be chasedall the way back to the Freakshop, butthe car has more than enough health to survive the trip.

NEXT:Grand Theft Auto Online: First Dose 3 - Fatal Incursion Walkthrough

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