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Collecting rare resources is a crucial part ofFallout 76,including tracking down the elusive glowing resin. This bioluminescent sap is found on the sides of trees throughout Appalachia and can be used in a variety of ways, from crafting consumables to enhancing weapon mods. However, collecting glowing resin can be tricky, if you don’t know what it looks like.
If you want to find glowing resin in Fallout 76, then we’ve got several premium locations for you to collect glowing resin. Once you’ve got your hands on a solid amount of this rare resin, you’ll be in business to craft some delicious food, Healing Salves, and even some unique weapon mods.
Updated July 10, 2025, by Andrew Scariati:Locating glowing resin in Fallout 76 is nearly impossible if you’re roaming Appalachia in the hope of stumbling across some. Instead, we’ve compiled some Fallout 76 glowing resin locations for you to browse and choose from when you’re ready to hunt down this scarce resource.
Whether you’rejoining after Fallout 76’s recent boomor are a veteran, these glowing resin locations are the best you’ll find.
The Best Locations To Find Glowing Resin
Glowing resin can be found almost anywhere outdoors in Fallout 76, but it is mostcommonly found on trees or near wood.
It appears asa vibrant yellow-orange substancegrowing on the sides of trees and can be harvested by approaching the tree and interacting with it.
Keep your eye out for any trees withorange glowing resinand examine them.
Glowing resin can be tough to spot,but it’s well worth the effort once you know what to look for.
Site Alpha
The Vantage
Aside from trees, look forsmall white bottlesscattered throughout Appalachia, whichalso contain glowing resin.
How To Use Glowing Resin
While glowing resin can be consumed raw to satisfy a small amount of hunger, it also comes witha medium dose of radiation and a chance for disease.
It’s best to cook it for additional benefits, likeimproved healingorincreased resistance to radiation.
Glowing resin can also be used to craft a variety of consumables, such assyruporvodka.
These consumables can give you a much-needed boost in the wasteland, from increased stamina toimproved damage resistance.
Script: Flavors of Mayhem
But the real prize for collecting glowing resin is using it to create one ofFallout 76’s best high-level weapon mods: theKarma syringe barrelmod forRose’s Syringer.
The Karma syringe barrel mod grants the following:
On paper, this mod’s first effect is a massive hindrance to you, as your target will become almost impossible to kill.
However,after their 30-second period of strength, you can easily decimate your now-weakened opponent with another weapon after swapping away from Rose’s Syringer.
The Syringer is more of a utility weapon and doesn’t have much use as a pure damage option, dealing only seven hit points of damage on its own.
However, using Rose’s Syringer in tandem withanother weapon can yield fantastic results,particularly against powerful single targets.
If you want to use Rose’s Syringer well, then try to hit your target from a distance with a sneak attack so youremain undetected while they’re buffed.
Then, after the 30-second buff expires, you can reveal yourself and defeat your weakened prey.
